{"id":6919,"date":"2021-01-15T06:01:08","date_gmt":"2021-01-14T21:01:08","guid":{"rendered":"http:\/\/www.hs-kyoto.net\/?p=6919"},"modified":"2026-04-28T11:41:14","modified_gmt":"2026-04-28T02:41:14","slug":"%e8%97%a4%e4%ba%95%e3%81%95%e3%82%93%e3%81%ae%e7%a0%94%e7%a9%b6%e3%81%8cplos-one-%e3%81%ab%e5%8f%97%e8%ab%be","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=6919","title":{"rendered":"\u30d2\u30c8\u80da\u306e\u6c17\u7ba1\u652f\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u30eb\u30fc\u30eb\u3067\u679d\u5206\u304b\u308c\u3059\u308b\u306e\u304b-\u4e09\u6b21\u5143\u518d\u69cb\u7bc9\u306b\u3088\u308b\u6c17\u7ba1\u652f\u306e\u5206\u5c90\u69d8\u5f0f\u306e\u89e3\u6790-"},"content":{"rendered":"\n<p>\u85e4\u4e95\u3055\u3093\u306f\u3001\u535a\u58eb\u8ab2\u7a0b\u306e\u7814\u7a76\u3067\u30d2\u30c8\u80da\u306e<strong>\u6c17\u7ba1\u652f\u6a39<\/strong>\u304c\u3069\u306e\u3088\u3046\u306a\u30eb\u30fc\u30eb\u3067\u679d\u5206\u304b\u308c\u3057\u3066\u3044\u304f\u306e\u304b\u3092\u3001<strong>\u4f4d\u76f8\u5deeX\u7ddaCT\u306b\u3088\u308b\u4e09\u6b21\u5143\u89e3\u6790<\/strong>\u306b\u3088\u3063\u3066\u8a73\u3057\u304f\u8abf\u3079\u307e\u3057\u305f\u3002<br>\u305d\u306e\u7d50\u679c\u3001\u80ba\u8449\u6c17\u7ba1\u652f\u304b\u3089\u533a\u57df\u6c17\u7ba1\u652f\u3001\u3055\u3089\u306b\u4e9c\u533a\u57df\u6c17\u7ba1\u652f\u306b\u3044\u305f\u308b\u307e\u3067\u3001<strong>\u5927\u90e8\u5206\u306e\u6c17\u7ba1\u652f\u306f\u300c\u5358\u8ef8\u6027\u5206\u5c90\uff08monopodial branching\uff09\u300d\u3067\u5f62\u6210\u3055\u308c\u308b<\/strong>\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<br>\u4e00\u65b9\u3067\u3001<strong>\u5de6\u4e0a\u8449\u6c17\u7ba1\u652f\u304b\u3089\u5206\u304b\u308c\u308b\u820c\u533a\u6c17\u7ba1\u652f<\/strong>\u3067\u306f\u3001\u4f8b\u5916\u7684\u306b**\u4e8c\u5206\u6027\u5206\u5c90\uff08dipodial branching\uff09**\u304c\u8a8d\u3081\u3089\u308c\u3001\u30d2\u30c8\u80ba\u306b\u7279\u5fb4\u7684\u306a\u5206\u5c90\u69d8\u5f0f\u306e\u4e00\u7aef\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012021\u5e741\u670815\u65e5\u306b <em>PLOS ONE<\/em> \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u80cc\u666f<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"232\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19-610x232.png\" alt=\"\" class=\"wp-image-14595\" style=\"width:450px\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19-610x232.png 610w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19-400x152.png 400w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19-115x44.png 115w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19-768x292.png 768w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2021\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-28-8.14.19.png 1098w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure>\n<\/div>\n\n\n<p>\u80ba\u3084\u814e\u81d3\u306e\u3088\u3046\u306a\u81d3\u5668\u306f\u3001\u679d\u5206\u304b\u308c\u3092\u7e70\u308a\u8fd4\u3057\u306a\u304c\u3089\u8907\u96d1\u306a\u7acb\u4f53\u69cb\u9020\u3092\u3064\u304f\u308a\u307e\u3059\u3002<br>\u3053\u3046\u3057\u305f**\u5206\u5c90\u5f62\u6210\uff08branching morphogenesis\uff09**\u306f\u3001\u81d3\u5668\u5f62\u6210\u306e\u57fa\u672c\u539f\u7406\u306e\u3072\u3068\u3064\u3067\u3042\u308a\u3001\u5148\u5929\u7570\u5e38\u306e\u7406\u89e3\u306b\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6c17\u7ba1\u652f\u306e\u5206\u5c90\u69d8\u5f0f\u3068\u3057\u3066\u306f\u3001\u4e3b\u306b\u6b21\u306e2\u3064\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5358\u8ef8\u6027\u5206\u5c90\uff08monopodial branching\uff09<\/strong><br>\u5b50\u679d\u304c\u89aa\u679d\u306e\u5074\u58c1\u304b\u3089\u51fa\u308b\u5206\u5c90<\/li>\n\n\n\n<li><strong>\u4e8c\u5206\u6027\u5206\u5c90\uff08dipodial branching\uff09<\/strong><br>\u89aa\u679d\u306e\u5148\u7aef\u304c\u4e8c\u80a1\u306b\u5206\u304b\u308c\u308b\u5206\u5c90<\/li>\n<\/ul>\n\n\n\n<p>\u30de\u30a6\u30b9\u80ba\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u5206\u5c90\u69d8\u5f0f\u304c\u7d44\u307f\u5408\u308f\u3055\u3063\u3066\u6c17\u7ba1\u652f\u6a39\u304c\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br>\u3057\u304b\u3057\u3001<strong>\u30d2\u30c8\u80da\u306e\u6c17\u7ba1\u652f\u3067\u3001\u3069\u306e\u5206\u5c90\u304c\u3069\u306e\u69d8\u5f0f\u306b\u3042\u305f\u308b\u306e\u304b<\/strong>\u306f\u3001\u3053\u308c\u307e\u3067\u5341\u5206\u306b\u660e\u3089\u304b\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u3067\u672c\u7814\u7a76\u3067\u306f\u3001\u30d2\u30c8\u80da\u80ba\u306e\u6c17\u7ba1\u652f\u6a39\u5168\u4f53\u3092\u4e09\u6b21\u5143\u518d\u69cb\u7bc9\u3057\u3001\u5404\u5206\u5c90\u90e8\u306e\u9577\u3055\u5909\u5316\u3092\u624b\u304c\u304b\u308a\u306b\u3001\u5206\u5c90\u69d8\u5f0f\u3092\u5b9a\u91cf\u7684\u306b\u5206\u985e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u65b9\u6cd5<\/h2>\n\n\n\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001\u4eac\u90fd\u5927\u5b66\u306e<strong>\u4eac\u90fd\u30b3\u30ec\u30af\u30b7\u30e7\u30f3<\/strong>\u306b\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b<strong>CS15\u301cCS23\u306e\u30d2\u30c8\u80da48\u4f8b<\/strong>\u3092\u5bfe\u8c61\u306b\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5404\u6a19\u672c\u306b\u3064\u3044\u3066\u3001<strong>\u4f4d\u76f8\u5deeX\u7ddaCT<\/strong>\u3067\u64ae\u5f71\u3057\u305f\u9ad8\u89e3\u50cf\u5ea6\u753b\u50cf\u3092\u3082\u3068\u306b\u3001\u6c17\u7ba1\u652f\u6a39\u3092\u4e09\u6b21\u5143\u518d\u69cb\u7bc9\u3057\u307e\u3057\u305f\u3002<br>\u89e3\u6790\u3067\u306f\u3001\u6c17\u7ba1\u652f\u306e\u5206\u5c90\u70b9\u3068\u679d\u306e\u4e2d\u5fc3\u7dda\u3092\u62bd\u51fa\u3057\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u80ba\u8449\u6c17\u7ba1\u652f<\/strong><\/li>\n\n\n\n<li><strong>\u533a\u57df\u6c17\u7ba1\u652f<\/strong><\/li>\n\n\n\n<li><strong>\u4e9c\u533a\u57df\u6c17\u7ba1\u652f<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3092\u5bfe\u8c61\u306b\u3001\u305d\u308c\u305e\u308c\u306e<strong>\u89aa\u679d\u306e\u9577\u3055<\/strong>\u3068<strong>\u5b50\u679d\u306e\u5f62\u6210\u524d\u5f8c\u306e\u5909\u5316<\/strong>\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5206\u5c90\u69d8\u5f0f\u306e\u5224\u5b9a\u3067\u306f\u3001\u5b50\u679d\u304c\u5f62\u6210\u3055\u308c\u305f\u5f8c\u306b\u89aa\u679d\u306e\u9577\u3055\u304c<strong>\u77ed\u304f\u306a\u308b\u304b\u3069\u3046\u304b<\/strong>\u3092\u57fa\u6e96\u306b\u3057\u307e\u3057\u305f\u3002<br>\u89aa\u679d\u306e\u5148\u7aef\u304c\u4e8c\u5206\u3055\u308c\u308b\u5834\u5408\u306f\u4e8c\u5206\u6027\u5206\u5c90\u3001\u5074\u58c1\u304b\u3089\u65b0\u305f\u306a\u679d\u304c\u51fa\u308b\u5834\u5408\u306f\u5358\u8ef8\u6027\u5206\u5c90\u3068\u89e3\u91c8\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e3b\u306a\u7d50\u679c<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u80ba\u8449\u6c17\u7ba1\u652f\u306f\u3001\u3059\u3079\u3066\u5358\u8ef8\u6027\u5206\u5c90\u3067\u5f62\u6210\u3055\u308c\u3066\u3044\u307e\u3057\u305f<\/h3>\n\n\n\n<p>\u89e3\u6790\u306e\u7d50\u679c\u3001<strong>\u80ba\u8449\u6c17\u7ba1\u652f<\/strong>\u306f\u3059\u3079\u3066<strong>\u5358\u8ef8\u6027\u5206\u5c90<\/strong>\u306b\u3088\u3063\u3066\u5f62\u6210\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<br>\u3064\u307e\u308a\u3001\u53f3\u4e0a\u8449\u30fb\u53f3\u4e2d\u8449\u30fb\u5de6\u4e0a\u8449\u306a\u3069\u306e\u80ba\u8449\u6c17\u7ba1\u652f\u306f\u3001\u89aa\u679d\u306e\u5148\u7aef\u304c\u4e8c\u80a1\u306b\u5206\u304b\u308c\u308b\u306e\u3067\u306f\u306a\u304f\u3001<strong>\u4e3b\u6c17\u7ba1\u652f\u306e\u5074\u58c1\u304b\u3089\u82bd\u306e\u3088\u3046\u306b\u51fa\u3066\u304f\u308b<\/strong>\u304b\u305f\u3061\u3067\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u53e4\u5178\u7684\u306a\u89b3\u5bdf\u306b\u3088\u308a\u793a\u5506\u3055\u308c\u3066\u3044\u305f\u6240\u898b\u3092\u3001\u4e09\u6b21\u5143\u5f62\u614b\u3068\u9577\u3055\u8a08\u6e2c\u306b\u3088\u3063\u3066\u5b9a\u91cf\u7684\u306b\u88cf\u3065\u3051\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. \u533a\u57df\u6c17\u7ba1\u652f\u30fb\u4e9c\u533a\u57df\u6c17\u7ba1\u652f\u306e\u5927\u90e8\u5206\u3082\u5358\u8ef8\u6027\u5206\u5c90\u3067\u3057\u305f<\/h3>\n\n\n\n<p>\u533a\u57df\u6c17\u7ba1\u652f\u304a\u3088\u3073\u4e9c\u533a\u57df\u6c17\u7ba1\u652f\u306b\u3064\u3044\u3066\u306f\u3001<strong>25\u304b\u6240\u306e\u5206\u5c90<\/strong>\u3092\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<br>\u305d\u306e\u7d50\u679c\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>22\u304b\u6240<\/strong>\u304c\u5358\u8ef8\u6027\u5206\u5c90<\/li>\n\n\n\n<li><strong>2\u304b\u6240<\/strong>\u306f\u660e\u78ba\u306b\u5206\u985e\u3067\u304d\u305a<\/li>\n\n\n\n<li><strong>1\u304b\u6240\u306e\u307f<\/strong>\u304c\u4e8c\u5206\u6027\u5206\u5c90<\/li>\n<\/ul>\n\n\n\n<p>\u3068\u5224\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3059\u306a\u308f\u3061\u3001<strong>\u5206\u985e\u53ef\u80fd\u3060\u3063\u305f\u5206\u5c90\u306e\u307b\u3068\u3093\u3069\u3059\u3079\u3066\u304c\u5358\u8ef8\u6027\u5206\u5c90<\/strong>\u3067\u3042\u308a\u3001\u30d2\u30c8\u80da\u306e\u8fd1\u4f4d\u6c17\u7ba1\u652f\u3067\u306f\u3001\u5358\u8ef8\u6027\u5206\u5c90\u304c\u57fa\u672c\u7684\u306a\u69d8\u5f0f\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3. 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class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8ad6\u6587\u60c5\u5831<\/h2>\n\n\n\n<p><strong>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><br><em>Bronchial tree of the human embryo: Categorization of the branching mode as monopodial and dipodial<\/em><\/p>\n\n\n\n<p><strong>\u8457\u8005<\/strong><br>Sena Fujii, Taiga Muranaka, Jun Matsubayashi, Shigehito Yamada, Akio Yoneyama, Tetsuya Takakuwa<\/p>\n\n\n\n<p><strong>\u63b2\u8f09\u8a8c<\/strong><br><em>PLOS ONE<\/em><\/p>\n\n\n\n<p><strong>\u516c\u958b\u65e5<\/strong><br>2021\u5e741\u670815\u65e5<\/p>\n\n\n\n<p><strong>DOI<\/strong><br><a class=\"\" href=\"https:\/\/doi.org\/10.1371\/journal.pone.0245558\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1371\/journal.pone.0245558<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 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