                                        {"id":4356,"date":"2015-01-09T20:12:12","date_gmt":"2015-01-09T11:12:12","guid":{"rendered":"http:\/\/www.hs-kyoto.net\/?p=4356"},"modified":"2026-01-15T22:16:36","modified_gmt":"2026-01-15T13:16:36","slug":"2014%e5%b9%b4%e5%ba%a6%e4%bf%ae%e5%a3%ab%e8%ab%96%e6%96%87%e3%81%ae%e6%a6%82%e8%a6%81-%e4%b8%8a%e9%87%8e%e6%b2%99%e5%ad%a3%ef%bc%89","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=4356","title":{"rendered":"2014\u5e74\u5ea6;\u4fee\u58eb\u8ad6\u6587\u6982\u8981 (\u4e0a\u91ce\uff09"},"content":{"rendered":"\n<p class=\"has-background has-medium-font-size wp-block-paragraph\" style=\"background-color:#faf0c3\"><strong>The digestive tract and derived primordium differentiate by following a precise timeline in early human embryos<br>\u30d2\u30c8\u4f53\u7bc0\u671f\u306b\u304a\u3051\u308b\u6d88\u5316\u7ba1\u3068\u305d\u306e\u7531\u6765\u539f\u57fa\u306e\u5206\u5316\u6642\u7cfb\u5217\u306e\u89e3\u6790\u3000<\/strong><br><strong>\u4e0a\u91ce\u6c99\u5b63<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"468\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2015\/01\/image.png\" alt=\"\" class=\"wp-image-14237\" style=\"aspect-ratio:1.3034331498142429;width:450px;height:auto\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2015\/01\/image.png 610w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2015\/01\/image-391x300.png 391w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2015\/01\/image-115x88.png 115w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">[\u80cc\u666f] \u30d2\u30c8\u306f\u53d7\u7cbe\u5f8c38\u9031\u3067\u51fa\u751f\u3057\u3001\u524d\u534a\u306e8\u9031\u9593\u306f\u80da\u5b50\u671f\u3068\u547c\u3070\u308c\u308b\u3002\u80da\u5b50\u671f\u306f\u5916\u8868\u306e\u5f62\u614b\u5b66\u7684\u7279\u5fb4\u3068\u5185\u90e8\u89b3\u5bdf\u306b\u57fa\u3065\u304d23\u6bb5\u968e\u306b\u5206\u985e\u3055\u308c\u3001\u3053\u308c\u3092Carnegie Stage (CS)\u3068\u3044\u3046\u3002CS9-13\u306e\u6bb5\u968e\u306f\u3001\u5f62\u6210\u3055\u308c\u305f\u4f53\u7bc0\u306e\u6570\u3067\u5b9a\u7fa9\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u306e\u3046\u3061CS12-13\u306f\u3001\u5375\u9ec4\u56a2\u306e\u9589\u9396\u304c\u9032\u307f\u6d88\u5316\u7ba1\u304c\u5f62\u6210\u3055\u308c\u3001\u80ba\u30fb\u809d\u81d3\u30fb\u81b5\u81d3\u30fb\u80c6\u56a2\u306a\u3069\u6d88\u5316\u7ba1\u7531\u6765\u306e\u5668\u5b98\u539f\u57fa\u304c\u767a\u751f\u30fb\u5206\u5316\u3059\u308b\u6642\u671f\u3067\u3042\u308b\u3002\u3053\u306e\u6642\u671f\u306e\u30d2\u30c8\u80da\u5b50\u306b\u3064\u3044\u3066\u306f\u7d44\u7e54\u89b3\u5bdf\u306b\u57fa\u3065\u304f\u69d8\u3005\u306a\u75c7\u4f8b\u5831\u544a\u304c\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u8907\u6570\u306e\u500b\u4f53\u9593\u3067\u306e\u5206\u5316\u72b6\u6cc1\u306b\u95a2\u3059\u308b\u6bd4\u8f03\u691c\u8a0e\u306f\u884c\u308f\u308c\u3066\u3044\u306a\u3044\u3002\u672c\u7814\u7a76\u3067\u306f\u3001CS12-13\u306b\u304a\u3051\u308b\u6d88\u5316\u7ba1\u53ca\u3073\u305d\u306e\u7531\u6765\u539f\u57fa\u306e\u7acb\u4f53\u69cb\u9020\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3068\u3068\u3082\u306b\u3001CS12-13\u306e\u671f\u9593\u3092\u7d30\u5206\u5316\u3057\u3001\u540c\u4e00CS\u306b\u76f8\u5f53\u3059\u308b\u500b\u4f53\u9593\u3067\u6d88\u5316\u7ba1\u3068\u7531\u6765\u539f\u57fa\u306e\u767a\u751f\u30fb\u5206\u5316\u306e\u6642\u7cfb\u5217\u3092\u6bd4\u8f03\u691c\u8a0e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[\u5bfe\u8c61\u3068\u65b9\u6cd5] CS11-13\u306b\u76f8\u5f53\u3059\u308b\u8a0842\u4f53\u306e\u30d2\u30c8\u80da\u5b50\u9023\u7d9a\u7d44\u7e54\u5207\u7247\u3092\u518d\u69cb\u7bc9\u3057\u3066\u7acb\u4f53\u50cf\u3092\u4f5c\u6210\u3057\u3001\u6d88\u5316\u7ba1\u5185\u8154\u3092\u63cf\u51fa\u3057\u3066\u305d\u306e\u5f62\u614b\u3092\u89b3\u5bdf\u3057\u305f\u3002\u54bd\u982d\u30fb\u80ba\u30fb\u80c3\u30fb\u809d\u81d3\u30fb\u81b5\u81d3\u9818\u57df\u306f\u7d44\u7e54\u89b3\u5bdf\u3092\u8ffd\u52a0\u3057\u3066\u884c\u3063\u305f\u3002\u5404\u500b\u4f53\u306e\u4f53\u7bc0\u306e\u6570\u3092\u8a08\u6e2c\u3057\u3001\u4f53\u7bc0\u756a\u53f7\u3092\u7528\u3044\u3066\u5404\u5668\u5b98\u539f\u57fa\u306e\u982d\u5c3e\u65b9\u5411\u306e\u4f4d\u7f6e\u3092\u691c\u8a0e\u3057\u305f\u3002CS12\u306f\u4f53\u7bc0\u6570\u3001CS13\u306f\u773c\u306e\u539f\u57fa\u306e\u767a\u751f\u30924\u6bb5\u968e (grade\u2160-\u2163)\u306b\u7d30\u5206\u5316\u3057\u305f\u3082\u306e\u3092\u6642\u9593\u7684\u6307\u6a19\u3068\u3057\u3001\u6d88\u5316\u7ba1\u3068\u7531\u6765\u539f\u57fa\u306e\u5206\u5316\u72b6\u6cc1\u3092\u89e3\u6790\u3057\u305f\u3002\u5916\u8868\u306b\u7570\u5e38\u306e\u307f\u3089\u308c\u308b6\u500b\u4f53\u306b\u3064\u3044\u3066\u3082\u540c\u69d8\u306b\u518d\u69cb\u7bc9\u3092\u884c\u3044\u3001\u6b63\u5e38\u500b\u4f53\u3067\u691c\u8a0e\u3057\u305f\u5206\u5316\u6642\u7cfb\u5217\u3068\u6bd4\u8f03\u3057\u3001\u6d88\u5316\u7ba1\u306e\u7570\u5e38\u306e\u6709\u7121\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[\u7d50\u679c] \u2460\u6d88\u5316\u7ba1\u3068\u5668\u5b98\u539f\u57fa\u306e\u5f62\u614b\u5909\u5316: \u6d88\u5316\u7ba1\u3067\u306f\u3001CS12\u306e\u4f53\u7bc0\u657024\u3067\u7db2\u56a2\u306e\u767a\u751f\u3001CS13\u306egrade\u2160\u30678\u3064\u306e\u54bd\u982d\u56a2\u306e\u767a\u751f\u3001grade\u2161\u3067\u80c3\u304c\u7d21\u9318\u578b\u306b\u5206\u5316\u3001\u4e2d\u8178\u30eb\u30fc\u30d7\u30fb\u5341\u4e8c\u6307\u8178\u30eb\u30fc\u30d7\u306e\u5f62\u6210\u304c\u89b3\u5bdf\u3055\u308c\u305f\u3002\u7531\u6765\u539f\u57fa\u3067\u306f\u3001CS12\u306e\u4f53\u7bc0\u657026\u3067\u80ba\u539f\u57fa\u306e\u767a\u751f\u3001\u4f53\u7bc0\u657027\u3067\u982d\u5074\u809d\u82bd\u306e\u5f62\u6210\u3001CS13\u306egrade\u2160\u3067\u80ba\u539f\u57fa\u306e\u5206\u5c90\u3001\u80cc\u5074\u81b5\u82bd\u539f\u57fa\u306e\u767a\u751f\u3001grade\u2161\u3067\u80c6\u56a2\u539f\u57fa\u306e\u767a\u751f\u3001grade\u2162\u3067\u6c17\u7ba1\u306e\u5206\u5316\u3001grade\u2163\u3067\u6c17\u7ba1\u306e\u6700\u95772\u4f53\u7bc0\u5206\u307e\u3067\u306e\u4f38\u9577\u304c\u89b3\u5bdf\u3055\u308c\u305f\u3002\u2461\u5668\u5b98\u539f\u57fa\u306e\u4f4d\u7f6e: \u80ba\u306f\u7b2c2\u4f53\u7bc0\u306e\u9ad8\u3055\u304b\u3089\u5c3e\u5074\u3078\u4e0b\u964d\u3057\u3001CS12\u306e\u4f53\u7bc0\u657026\u4ee5\u964d\u306f\u7b2c4\u4f53\u7bc0\u4ed8\u8fd1\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u305f\u3002CS13\u306egrade\u2162\u3067\u306e\u6c17\u7ba1\u5206\u5316\u5f8c\u3082\u3001\u6c17\u7ba1\u3068\u98df\u9053\u306e\u5206\u5c90\u70b9\u306f\u7b2c4\u4f53\u7bc0\u306e\u9ad8\u3055\u306b\u4f4d\u7f6e\u3057\u3066\u304a\u308a\u3001\u500b\u4f53\u5dee\u306f\u307b\u307c\u306a\u304b\u3063\u305f\u3002CS12\u3067\u306f\u80c3\u30fb\u809d\u81d3\u304c4\u4f53\u7bc0\u307b\u3069\u4e0b\u964d\u3057\u3066\u3044\u305f\u304c\u3001CS13\u3067\u306f1\u4f53\u7bc0\u5206\u306e\u4e0b\u964d\u306b\u3068\u3069\u307e\u308a\u3001\u80cc\u5074\u81b5\u82bd\u30fb\u80c6\u56a2\u3082\u809d\u81d3\u306b\u8fd1\u63a5\u3057\u3066\u4e0b\u964d\u3057\u3066\u3044\u305f\u3002\u2462\u7570\u5e38\u500b\u4f53\u306e\u89e3\u6790: \u7570\u5e38\u500b\u4f536\u4f8b\u4e2d4\u4f8b\u306f\u6d88\u5316\u7ba1\u306b\u7570\u5e38\u304c\u89b3\u5bdf\u3055\u308c\u305a\u3001\u305d\u306e\u7279\u5fb4\u306f\u4f5c\u6210\u3057\u305f\u5206\u5316\u6642\u7cfb\u5217\u3068\u4e00\u81f4\u3057\u305f\u30021\u4f8b\u306f\u80ba\u539f\u57fa\u3068\u4e2d\u8178\u9818\u57df\u3001\u3082\u30461\u4f8b\u306f\u809d\u81d3\u539f\u57fa\u306b\u5206\u5316\u6642\u7cfb\u5217\u306b\u3042\u3066\u306f\u307e\u3089\u306a\u3044\u5f62\u614b\u7570\u5e38\u304c\u691c\u51fa\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[\u8003\u5bdf] \u80da\u5b50\u306e\u4f53\u7bc0\u6570\u53ca\u3073\u7d30\u5206\u5316\u3057\u305f\u767a\u751f\u6bb5\u968e\u3068\u3001\u6d88\u5316\u7ba1\u3068\u7531\u6765\u539f\u57fa\u306e\u767a\u751f\u30fb\u5206\u5316\u6642\u671f\u3068\u306f\u95a2\u9023\u6027\u304c\u307f\u3089\u308c\u305f\u3002CS12-13\u306e\u6d88\u5316\u7ba1\u306e\u767a\u751f\u3068\u5206\u5316\u306f\u5f93\u6765\u8003\u3048\u3089\u308c\u3066\u3044\u305f\u3088\u308a\u3082\u7cbe\u78ba\u306b\u9032\u884c\u3057\u3066\u304a\u308a\u3001\u500b\u4f53\u5dee\u304c\u5c11\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u4eca\u56de\u6b63\u5e38\u500b\u4f53\u306e\u89b3\u5bdf\u304b\u3089\u5f97\u3089\u308c\u305f\u5206\u5316\u6642\u7cfb\u5217\u3092\u53c2\u7167\u3057\u3066\u3001\u5916\u8868\u7570\u5e38\u306e\u500b\u4f53\u306b\u304a\u3044\u3066\u6d88\u5316\u7ba1\u306e\u767a\u9054\u7570\u5e38\u3092\u691c\u51fa\u3067\u304d\u305f\u3002\u3053\u306e\u6642\u7cfb\u5217\u89e3\u6790\u306f\u3001\u6d88\u5316\u7ba1\u306b\u95a2\u3059\u308b\u7570\u5e38\u306e\u65e9\u671f\u767a\u898b\u3078\u306e\u6709\u7528\u6027\u304c\u898b\u8fbc\u307e\u308c\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">22. Ueno S, Yamada S, Uwabe C, M\u00e4nner J, Shiraki N, Takakuwa T, The digestive tract and derived primordia differentiate by following a precise timeline in human embryos between Carnegie stages 11 and 13, Anat Rec (Hoboken) 2016, &nbsp;299,&nbsp;439-449,&nbsp;DOI:&nbsp;10.1002\/ar.23314s,&nbsp;&nbsp;<a href=\"http:\/\/www.hs-kyoto.net\/?p=4356\">(\u6982\u8981)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The digestive tract and derived primordium differentiate by following a precise timeline in early human embryo [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14237,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,19],"tags":[],"class_list":["post-4356","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-36","category-19"],"_links":{"self":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4356","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4356"}],"version-history":[{"count":10,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4356\/revisions"}],"predecessor-version":[{"id":14239,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4356\/revisions\/14239"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/media\/14237"}],"wp:attachment":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4356"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4356"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4356"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}