{"id":14276,"date":"2026-03-06T14:03:55","date_gmt":"2026-03-06T05:03:55","guid":{"rendered":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=14276"},"modified":"2026-04-18T09:45:26","modified_gmt":"2026-04-18T00:45:26","slug":"%e9%a0%88%e8%97%a4%e3%81%95%e3%82%93%e3%81%ae%e4%bf%ae%e5%a3%ab%e8%ab%96%e6%96%87%e3%81%9d%e3%81%ae1%ef%bc%89%e3%81%8cnmr-in-biomed-%e3%81%ab%e5%8f%97%e8%ab%be","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=14276","title":{"rendered":"\u30d2\u30c8\u306e\u820c\u306e\u7b4b\u8089\u306f\u3001\u3044\u3064\u30fb\u3069\u306e\u3088\u3046\u306b\u3067\u304d\u3066\u3044\u304f\u306e\u304b-\u767a\u751f\u671f\u306e\u7b4b\u7dda\u7dad\u306e\u5411\u304d\u3092\u53ef\u8996\u5316-"},"content":{"rendered":"\n<p><strong>\u4fee\u58eb\uff12\u5e74\u751f\u306e\u9808\u85e4\u3055\u3093<\/strong>\u304c\u3001\u30d2\u30c8\u306e\u767a\u751f\u904e\u7a0b\u306b\u304a\u3051\u308b<strong>\u820c\u306e\u7b4b\u8089\u306e\u5f62\u6210<\/strong>\u3092\u3001<strong>\u62e1\u6563\u30c6\u30f3\u30bd\u30eb\u753b\u50cf\u6cd5\uff08DTI: Diffusion Tensor Imaging\uff09\u3092\u7528\u3044\u3066\u89e3\u6790\u3057\u3001\u820c\u306e\u5185\u5728\u7b4b<\/strong>\u3068<strong>\u5916\u5728\u7b4b<\/strong>\u304c\u3001\u3053\u308c\u307e\u3067\u8003\u3048\u3089\u308c\u3066\u3044\u305f\u3088\u3046\u306b\u5927\u304d\u304f\u6642\u671f\u3092\u305a\u3089\u3057\u3066\u5206\u5316\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001<strong>\u521d\u671f\u306b\u306f\u307b\u307c\u540c\u3058\u6642\u671f\u306b\u5206\u5316\u3092\u59cb\u3081\u308b<\/strong>\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012026\u5e743\u67085\u65e5\u306b <em>NMR in Biomedicine<\/em> \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u80cc\u666f<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"514\" src=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03-610x514.png\" alt=\"\" class=\"wp-image-14282\" style=\"aspect-ratio:1.1867882542868362;width:450px;height:auto\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03-610x514.png 610w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03-356x300.png 356w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03-115x97.png 115w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03-768x648.png 768w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/01\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-01-15-7.13.03.png 1262w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure>\n<\/div>\n\n\n<p>\u820c\u306f\u3001\u98df\u3079\u308b\u3001\u98f2\u307f\u8fbc\u3080\u3001\u8a71\u3059\u3068\u3044\u3063\u305f\u8907\u96d1\u306a\u904b\u52d5\u3092\u652f\u3048\u308b\u91cd\u8981\u306a\u5668\u5b98\u3067\u3001\u8907\u6570\u306e\u7b4b\u8089\u304b\u3089\u3067\u304d\u3066\u3044\u307e\u3059\u3002<br>\u3053\u308c\u3089\u306e\u7b4b\u8089\u306f\u5927\u304d\u304f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u820c\u306e\u4e2d\u3067\u59cb\u307e\u308a\u820c\u306e\u4e2d\u3067\u7d42\u308f\u308b<strong>\u5185\u5728\u7b4b<\/strong><\/li>\n\n\n\n<li>\u5916\u304b\u3089\u820c\u306b\u5165\u308a\u8fbc\u307f\u3001\u820c\u306e\u4f4d\u7f6e\u3092\u5909\u3048\u308b<strong>\u5916\u5728\u7b4b<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u306b\u5206\u3051\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u767a\u751f\u9014\u4e2d\u306e\u30d2\u30c8\u306e\u820c\u3067\u306f\u3001\u7b4b\u8089\u3069\u3046\u3057\u304c\u975e\u5e38\u306b\u5bc6\u306b\u5165\u308a\u7d44\u3093\u3067\u304a\u308a\u3001\u901a\u5e38\u306e\u7d44\u7e54\u5207\u7247\u3060\u3051\u3067\u306f\u500b\u3005\u306e\u7b4b\u8089\u3092\u6b63\u78ba\u306b\u898b\u5206\u3051\u308b\u3053\u3068\u304c\u7c21\u5358\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br>\u305d\u306e\u305f\u3081\u3001\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u306f\u3001<strong>\u5185\u5728\u7b4b\u3068\u5916\u5728\u7b4b\u3067\u5206\u5316\u306e\u6642\u671f\u304c\u9055\u3046<\/strong>\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u5b9f\u969b\u306b\u306f\u300c\u898b\u5206\u3051\u306b\u304f\u3055\u300d\u304c\u305d\u306e\u89e3\u91c8\u306b\u5f71\u97ff\u3057\u3066\u3044\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u3067\u672c\u7814\u7a76\u3067\u306f\u3001\u6c34\u5206\u5b50\u306e\u62e1\u6563\u306e\u5411\u304d\u304b\u3089\u7d44\u7e54\u5185\u306e\u7dda\u7dad\u8d70\u884c\u3092\u63a8\u5b9a\u3067\u304d\u308b<strong>DTI<\/strong>\u3092\u7528\u3044\u3066\u3001\u767a\u751f\u671f\u306e\u30d2\u30c8\u306e\u820c\u306e\u7b4b\u7dda\u7dad\u306e\u5411\u304d\u3092\u4e09\u6b21\u5143\u7684\u306b\u8ffd\u8de1\u3057\u3001\u7b4b\u8089\u5f62\u6210\u306e\u904e\u7a0b\u3092\u8a73\u3057\u304f\u8abf\u3079\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u65b9\u6cd5<\/h2>\n\n\n\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001<strong>\u30d2\u30c8\u80da\u30fb\u80ce\u5150\u6a19\u672c29\u4f8b<\/strong>\u3092\u5bfe\u8c61\u306b\u3001<strong>7\u30c6\u30b9\u30e9MRI<\/strong>\u3092\u7528\u3044\u3066T1\u5f37\u8abf\u753b\u50cf\u3068DTI\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3057\u307e\u3057\u305f\u3002<br>\u3055\u3089\u306b\u3001\u4e00\u90e8\u306e\u6a19\u672c\u3067\u306f<strong>\u9023\u7d9a\u7d44\u7e54\u5207\u7247<\/strong>\u3092\u4f5c\u88fd\u3057\u3001MRI\u30fbDTI\u306e\u6240\u898b\u3068\u6bd4\u8f03\u3057\u306a\u304c\u3089\u3001\u5b9f\u969b\u306b\u3069\u306e\u6bb5\u968e\u3067\u7b4b\u7d44\u7e54\u304c\u533a\u5225\u3067\u304d\u308b\u304b\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>DTI\u3067\u306f\u3001\u820c\u306e\u4e2d\u3092\u8d70\u308b\u7b4b\u7dda\u7dad\u306e\u5411\u304d\u3092<strong>tractography<\/strong>\u3067\u53ef\u8996\u5316\u3057\u3001\u5404\u7b4b\u306e\u5411\u304d\u3084\u5e83\u304c\u308a\u65b9\u3001\u3055\u3089\u306b**FA\uff08fractional anisotropy\uff09<strong>\u3084<\/strong>MD\uff08mean diffusivity\uff09**\u3068\u3044\u3063\u305f\u6307\u6a19\u3082\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e3b\u306a\u7d50\u679c<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u820c\u306e\u7b4b\u7dda\u7dad\u306fCS19\u3067\u521d\u3081\u3066\u660e\u77ad\u306b\u6349\u3048\u3089\u308c\u307e\u3057\u305f<\/h3>\n\n\n\n<p>\u89e3\u6790\u306e\u7d50\u679c\u3001<strong>CS18<\/strong>\u3067\u306f\u820c\u306f\u307e\u3060\u5c0f\u3055\u306a\u584a\u3068\u3057\u3066\u898b\u3048\u308b\u6bb5\u968e\u3067\u3001\u660e\u77ad\u306a\u7b4b\u7dda\u7dad\u306e\u8d70\u884c\u306f\u78ba\u8a8d\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<br>\u4e00\u65b9\u3001<strong>CS19<\/strong>\u306b\u306a\u308b\u3068\u3001DTI\u3067\u7b4b\u7dda\u7dad\u306e\u65b9\u5411\u6027\u304c\u521d\u3081\u3066\u6349\u3048\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u820c\u7b4b\u306e\u5206\u5316\u304c\u59cb\u307e\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u7d44\u7e54\u5b66\u7684\u306b\u3082\u3001**CS18\u3067\u306f\u7b4b\u82bd\u7d30\u80de\uff08myoblast\uff09**\u304c\u89b3\u5bdf\u3055\u308c\u3001<strong>CS19\u3067\u306f\u7b4b\u7ba1\uff08myotubule\uff09\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<br>\u3064\u307e\u308a\u3001DTI\u306f\u3001\u3053\u3046\u3057\u305f\u3054\u304f\u521d\u671f\u306e\u672a\u719f\u306a\u7b4b\u7d44\u7e54<\/strong>\u3082\u691c\u51fa\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. \u5185\u5728\u7b4b\u3068\u5916\u5728\u7b4b\u306f\u3001\u521d\u671f\u306b\u306f\u307b\u307c\u540c\u3058\u6642\u671f\u306b\u5206\u5316\u3057\u3066\u3044\u307e\u3057\u305f<\/h3>\n\n\n\n<p>\u3053\u308c\u307e\u3067\u3001\u5916\u5728\u7b4b\u306e\u65b9\u304c\u5185\u5728\u7b4b\u3088\u308a\u5148\u306b\u5206\u5316\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3057\u305f\u3002<br>\u3057\u304b\u3057\u672c\u7814\u7a76\u3067\u306f\u3001<strong>CS19\u306e\u6642\u70b9\u3067\u3001\u5185\u5728\u7b4b\u306b\u3042\u305f\u308b\u5782\u76f4\u7b4b\u30fb\u6a2a\u7b4b\u3068\u3001\u5916\u5728\u7b4b\u306b\u3042\u305f\u308b\u30aa\u30c8\u30ac\u30a4\u820c\u7b4b\u30fb\u820c\u9aa8\u820c\u7b4b\u3092\u3044\u305a\u308c\u3082\u78ba\u8a8d<\/strong>\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7d50\u679c\u306f\u3001<strong>\u5185\u5728\u7b4b\u3068\u5916\u5728\u7b4b\u306f\u3001\u5c11\u306a\u304f\u3068\u3082\u7b4b\u82bd\u7d30\u80de\u304b\u3089\u7b4b\u7ba1\u3078\u79fb\u884c\u3059\u308b\u521d\u671f\u6bb5\u968e\u3067\u306f\u3001\u307b\u307c\u540c\u3058\u6642\u9593\u8ef8\u3067\u5206\u5316\u3059\u308b<\/strong>\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3. 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class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8ad6\u6587\u60c5\u5831<\/h2>\n\n\n\n<p><strong>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><br><em>Detection of Muscle Fiber Orientation During Human Tongue Development: Analysis Using Diffusion Tensor Imaging<\/em><\/p>\n\n\n\n<p><strong>\u8457\u8005<\/strong><br>Saho Suto, Toru Kanahashi, Sena Fujii, Hirohiko Imai, Hiroki Otani, Shigehito Yamada, Tetsuya Takakuwa<\/p>\n\n\n\n<p><strong>\u63b2\u8f09\u8a8c<\/strong><br><em>NMR in Biomedicine<\/em><\/p>\n\n\n\n<p><strong>\u516c\u958b\u65e5<\/strong><br>2026\u5e743\u67085\u65e5<\/p>\n\n\n\n<p><strong>DOI<\/strong><br><a class=\"\" href=\"https:\/\/doi.org\/10.1002\/nbm.70257\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/nbm.70257<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 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