{"id":13725,"date":"2026-02-03T05:20:16","date_gmt":"2026-02-02T20:20:16","guid":{"rendered":"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=13725"},"modified":"2026-04-15T16:20:25","modified_gmt":"2026-04-15T07:20:25","slug":"%e7%9f%b3%e5%b7%9d%e3%81%95%e3%82%93%e3%81%ae%e7%a0%94%e7%a9%b6%e3%81%8cplos-one%e3%81%ab%e5%8f%97%e8%ab%be","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=13725","title":{"rendered":"\u30d2\u30c8\u306e\u819d\u95a2\u7bc0\u306f\u3001\u80ce\u5150\u671f\u306e\u52d5\u304d\u3068\u3068\u3082\u306b\u3069\u306e\u3088\u3046\u306b\u5f62\u3065\u304f\u3089\u308c\u308b\u306e\u304b"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">\u5927\u817f\u7b4b\u3068\u819d\u84cb\u5927\u817f\u95a2\u7bc0\u306e\u7acb\u4f53\u89e3\u6790\u304b\u3089\u3001\u819d\u306e\u5f62\u614b\u5f62\u6210\u904e\u7a0b\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f<\/h1>\n\n\n\n<p>\u535a\u58eb\u5f8c\u671f\u8ab2\u7a0b\u306e\u77f3\u5ddd\u3055\u3093\u304c\u3001\u30d2\u30c8\u306e\u80da\u30fb\u80ce\u5150\u671f\u306b\u304a\u3051\u308b<strong>\u819d\u95a2\u7bc0\u306e\u5f62\u3065\u304f\u308a<\/strong>\u3068<strong>\u5927\u817f\u306e\u7b4b\u767a\u9054<\/strong>\u3092\u4e09\u6b21\u5143\u7684\u306b\u89e3\u6790\u3057\u3001\u819d\u84cb\u9aa8\u304c\u6ed1\u308b\u5927\u817f\u9aa8\u9060\u4f4d\u7aef\u306e\u6e9d\uff08<strong>trochlear groove<\/strong>\uff09\u306e\u5f62\u304c\u3001\u80ce\u5150\u306e\u6210\u9577\u3068\u3068\u3082\u306b\u3069\u306e\u3088\u3046\u306b\u6574\u3063\u3066\u3044\u304f\u306e\u304b\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<br>\u3055\u3089\u306b\u3001\u7b4b\u91cf\u3084\u95a2\u7bc0\u904b\u52d5\u306e\u6307\u6a19\u304c\u5897\u52a0\u3059\u308b\u6642\u671f\u3068\u3001\u6e9d\u306e\u89d2\u5ea6\u304c\u5b89\u5b9a\u3059\u308b\u6642\u671f\u304c\u8fd1\u3044\u3053\u3068\u304b\u3089\u3001<strong>\u80ce\u5150\u306e\u904b\u52d5\u3084\u7b4b\u767a\u9054\u304c\u819d\u95a2\u7bc0\u5f62\u614b\u306e\u6210\u719f\u306b\u95a2\u308f\u308b\u53ef\u80fd\u6027<\/strong>\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012026\u5e742\u67082\u65e5\u306b <em>PLOS ONE<\/em> \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u80cc\u666f<\/h2>\n\n\n\n<p>\u819d\u95a2\u7bc0\u306f\u3001\u5927\u817f\u9aa8\u30fb\u811b\u9aa8\u30fb\u819d\u84cb\u9aa8\u3001\u305d\u3057\u3066\u5468\u56f2\u306e\u7b4b\u30fb\u9771\u5e2f\u306a\u3069\u304b\u3089\u306a\u308b\u3001\u975e\u5e38\u306b\u8907\u96d1\u306a\u4e09\u6b21\u5143\u69cb\u9020\u3067\u3059\u3002<br>\u305d\u306e\u306a\u304b\u3067\u3082\u3001<strong>\u5927\u817f\u9aa8\u524d\u9762\u306e\u6ed1\u8eca\u6e9d\uff08trochlear groove\uff09\u306f\u3001\u819d\u84cb\u9aa8\u306e\u5b89\u5b9a\u6027\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u69cb\u9020\u3067\u3042\u308a\u3001\u3053\u306e\u6e9d\u306e\u5f62\u6210\u7570\u5e38\u306f\u819d\u84cb\u9aa8\u4e0d\u5b89\u5b9a\u75c7<\/strong>\u3084<strong>\u819d\u84cb\u5927\u817f\u95a2\u7bc0\u969c\u5bb3<\/strong>\u3068\u95a2\u4fc2\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u80ce\u5150\u306e\u904b\u52d5\u306b\u3088\u308b\u529b\u5b66\u7684\u523a\u6fc0\u304c\u3001\u9aa8\u3084\u95a2\u7bc0\u306e\u6b63\u5e38\u306a\u767a\u751f\u306b\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u306f\u3001\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u304b\u3089\u793a\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002<br>\u3057\u304b\u3057\u3001<strong>\u30d2\u30c8\u306e\u767a\u751f\u904e\u7a0b\u306b\u304a\u3044\u3066\u3001\u819d\u95a2\u7bc0\u306e\u5f62\u614b\u5f62\u6210\u3068\u7b4b\u767a\u9054\u30fb\u95a2\u7bc0\u904b\u52d5\u304c\u3069\u306e\u3088\u3046\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u306e\u304b<\/strong>\u306b\u3064\u3044\u3066\u306f\u3001\u5341\u5206\u306b\u5206\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u3067\u672c\u7814\u7a76\u3067\u306f\u3001\u80da\u671f\u304b\u3089\u80ce\u5150\u671f\u306b\u304b\u3051\u3066\u306e\u30d2\u30c8\u6a19\u672c\u3092\u7528\u3044\u3066\u3001\u819d\u95a2\u7bc0\u5468\u56f2\u306e\u9aa8\u683c\u3068\u7b4b\u3092\u4e09\u6b21\u5143\u7684\u306b\u518d\u69cb\u7bc9\u3057\u3001\u819d\u306e\u5f62\u614b\u5f62\u6210\u3092<strong>\u904b\u52d5\u5b66\u7684\u306a\u8996\u70b9<\/strong>\u304b\u3089\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u306e\u65b9\u6cd5<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"464\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-610x464.png\" alt=\"\" class=\"wp-image-14430\" style=\"aspect-ratio:1.3147031426190126;width:400px;height:auto\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-610x464.png 610w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-394x300.png 394w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-115x87.png 115w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-768x584.png 768w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-1536x1168.png 1536w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2026\/02\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2026-04-15-15.37.28-2048x1558.png 2048w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure>\n<\/div>\n\n\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001<strong>\u30d2\u30c8\u80da\u30fb\u80ce\u5150\u6a19\u672c29\u4f8b<\/strong>\u3092\u5bfe\u8c61\u306b\u3001<strong>\u4f4d\u76f8\u5deeX\u7ddaCT<\/strong>\u304a\u3088\u3073<strong>MRI<\/strong>\u3092\u7528\u3044\u3066\u4e0b\u80a2\u3001\u3068\u304f\u306b\u819d\u95a2\u7bc0\u5468\u56f2\u306e\u69cb\u9020\u3092\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u4e09\u6b21\u5143\u518d\u69cb\u7bc9\u3067\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5927\u817f\u9aa8<\/strong><\/li>\n\n\n\n<li><strong>\u811b\u9aa8<\/strong><\/li>\n\n\n\n<li><strong>\u819d\u84cb\u9aa8<\/strong><\/li>\n\n\n\n<li><strong>\u5927\u817f\u56db\u982d\u7b4b<\/strong><\/li>\n\n\n\n<li><strong>\u30cf\u30e0\u30b9\u30c8\u30ea\u30f3\u30b0\u30b9<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u306a\u3069\u3092\u500b\u5225\u306b\u63cf\u51fa\u3057\u3001\u819d\u95a2\u7bc0\u306e\u6210\u9577\u306b\u4f34\u3046\u5f62\u614b\u5909\u5316\u3092\u8abf\u3079\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u819d\u84cb\u9aa8\u304c\u63a5\u3059\u308b\u5927\u817f\u9aa8\u9060\u4f4d\u7aef\u306e<strong>\u6ed1\u8eca\u6e9d\u89d2\u5ea6<\/strong>\u3092\u8a08\u6e2c\u3057\u3001\u305d\u306e\u7d4c\u6642\u7684\u5909\u5316\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<br>\u307e\u305f\u3001\u7b4b\u306e\u4f53\u7a4d\u3084\u9577\u3055\u3001\u7b4b\u306e\u4f5c\u7528\u7dda\u304b\u3089\u3001\u819d\u95a2\u7bc0\u306b\u50cd\u304f\u529b\u3092\u53cd\u6620\u3059\u308b<strong>\u4eee\u60f3\u7684\u306a\u95a2\u7bc0\u904b\u52d5\u6307\u6a19<\/strong>\u3092\u7b97\u51fa\u3057\u3001\u95a2\u7bc0\u5f62\u614b\u3068\u306e\u95a2\u4fc2\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<br>\u3055\u3089\u306b\u3001\u5f62\u306e\u5909\u5316\u3092\u5ba2\u89b3\u7684\u306b\u6349\u3048\u308b\u305f\u3081\u306b\u3001<strong>Procrustes\u89e3\u6790<\/strong>\u3084<strong>\u4e3b\u6210\u5206\u5206\u6790<\/strong>\u3082\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e3b\u306a\u7d50\u679c<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u819d\u306e\u6ed1\u8eca\u6e9d\u306f\u3001\u80ce\u5150\u306e\u6210\u9577\u3068\u3068\u3082\u306b\u6df1\u304f\u306a\u308a\u3001\u7d04120 mm CRL\u3067\u5b89\u5b9a\u3057\u307e\u3057\u305f<\/h3>\n\n\n\n<p>\u89e3\u6790\u306e\u7d50\u679c\u3001\u5927\u817f\u9aa8\u306e\u6ed1\u8eca\u6e9d\u89d2\u5ea6\u306f\u3001**CRL 26.8 mm\u3054\u308d\u3067\u306f\u7d04160\u00b0**\u3068\u6d45\u3044\u5f62\u3067\u3057\u305f\u304c\u3001\u6210\u9577\u306b\u4f34\u3063\u3066\u5f90\u3005\u306b\u5c0f\u3055\u304f\u306a\u308a\u3001<strong>\u7d04120 mm CRL\u3067130\u00b0\u524d\u5f8c\u306b\u9054\u3057\u305f\u5f8c\u306f\u307b\u307c\u4e00\u5b9a<\/strong>\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u767a\u751f\u306e\u65e9\u3044\u6642\u671f\u306b\u306f\u6bd4\u8f03\u7684\u5e73\u5766\u3060\u3063\u305f\u819d\u524d\u9762\u306e\u5f62\u304c\u3001\u80ce\u5150\u306e\u6210\u9577\u3068\u3068\u3082\u306b<strong>\u3088\u308a\u6210\u4eba\u306b\u8fd1\u3044\u6e9d\u69cb\u9020\u3078\u3068\u6574\u3063\u3066\u3044\u304f<\/strong>\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u5225\u306e\u65ad\u9762\u3067\u8a55\u4fa1\u3057\u305f\u89d2\u5ea6\u306f\u521d\u671f\u304b\u3089\u304a\u304a\u3080\u306d\u4e00\u5b9a\u3067\u3042\u308a\u3001\u819d\u95a2\u7bc0\u306e\u5404\u90e8\u4f4d\u304c<strong>\u4e00\u69d8\u306b\u540c\u3058\u30da\u30fc\u30b9\u3067\u5f62\u3065\u304f\u3089\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u3044<\/strong>\u3053\u3068\u3082\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. \u5916\u5074\u5927\u817f\u9846\u306e\u7a81\u51fa\u304c\u3001\u80ce\u5150\u671f\u306b\u304b\u3051\u3066\u3088\u308a\u660e\u77ad\u306b\u306a\u308a\u307e\u3057\u305f<\/h3>\n\n\n\n<p>\u5f62\u614b\u89e3\u6790\u306e\u7d50\u679c\u3001\u6ed1\u8eca\u6e9d\u305d\u306e\u3082\u306e\u304c\u6df1\u304f\u306a\u308b\u3060\u3051\u3067\u306a\u304f\u3001<strong>\u5916\u5074\u5927\u817f\u9846\u306e\u7a81\u51fa<\/strong>\u304c\u6210\u9577\u3068\u3068\u3082\u306b\u3088\u308a\u660e\u77ad\u306b\u306a\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<br>\u3053\u308c\u306f\u3001\u819d\u84cb\u9aa8\u306e\u5b89\u5b9a\u6027\u306b\u91cd\u8981\u3068\u3055\u308c\u308b\u5916\u5074\u306e\u9ad8\u307e\u308a\u304c\u3001\u51fa\u751f\u524d\u304b\u3089\u5f62\u6210\u3055\u308c\u3066\u3044\u304f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3. 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class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8ad6\u6587\u60c5\u5831<\/h2>\n\n\n\n<p><strong>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><br><em>Morphogenetic development of trochlear groove and thigh muscles from embryo to fetus in humans<\/em><\/p>\n\n\n\n<p><strong>\u8457\u8005<\/strong><br>Aoi Ishikawa, Momoko Nagai-Tanima, Kanon Ishida, Hirohiko Imai, Akio Yoneyama, Shigehito Yamada, Hiroki Otani, Tomoki Aoyama, Tetsuya Takakuwa<\/p>\n\n\n\n<p><strong>\u63b2\u8f09\u8a8c<\/strong><br><em>PLOS ONE<\/em><\/p>\n\n\n\n<p><strong>\u516c\u958b\u65e5<\/strong><br>2026\u5e742\u67082\u65e5<\/p>\n\n\n\n<p><strong>DOI<\/strong><br><a class=\"\" href=\"https:\/\/doi.org\/10.1371\/journal.pone.0339167\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1371\/journal.pone.0339167<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 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