{"id":1367,"date":"2010-02-27T12:06:02","date_gmt":"2010-02-27T03:06:02","guid":{"rendered":"http:\/\/www.hs-kyoto.net\/?p=1367"},"modified":"2026-01-15T22:17:43","modified_gmt":"2026-01-15T13:17:43","slug":"2009-%e4%bf%ae%e5%a3%ab%e8%ab%96%e6%96%87","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=1367","title":{"rendered":"2009\u5e74\u5ea6\uff1b\u4fee\u58eb\u8ad6\u6587\u6982\u8981\uff08\u91d1\u8c37\u3001\u4e38\u5c71\uff09"},"content":{"rendered":"\n<p class=\"has-background has-medium-font-size wp-block-paragraph\" style=\"background-color:#faf0c3\"><strong>\u764cHras1\u907a\u4f1d\u5b50\u306fSL\/Kh\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u30ea\u30f3\u30d1\u816b\u767a\u75c7\u6642\u306b\u307f\u3089\u308c\u308b<\/strong><br><strong>\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u633f\u5165\u597d\u767a\u90e8\u4f4d\u306e\u3072\u3068\u3064\u3067\u3042\u308b<\/strong>\u3000\u91d1\u8c37\u548c\u54c9<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"140\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image-1.jpeg\" alt=\"\" class=\"wp-image-14258\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image-1.jpeg 300w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image-1-115x54.jpeg 115w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-left wp-block-paragraph\">SL\/Kh\u30de\u30a6\u30b9\u306fproto-SL\u3001AKR\u3092progenitor\u3068\u3059\u308b\u8fd1\u4ea4\u7cfb\u30de\u30a6\u30b9\u3067\u300190\uff05\u4ee5\u4e0a\u304c6\u30ab\u6708\u9f62\u4ee5\u5185\u306bpre-B\u30ea\u30f3\u30d1\u816b\u3092\u81ea\u7136\u767a\u75c7\u3059\u308b\u3002\u3053\u306e\u30de\u30a6\u30b9\u306f\u907a\u4f1d\u7684\u306b\u5185\u5728\u6027\u30de\u30a6\u30b9\u767d\u8840\u75c5\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u306e\u3072\u3068\u3064\u3067\u3042\u308bAKV-1\u306e\u633f\u5165\u3092\u7372\u5f97\u3057\u3066\u3044\u308b\u3002SL\/Kh\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30ea\u30f3\u30d1\u816b\u767a\u75c7\u306b\u304a\u3044\u3066\u3001\u30d7\u30ed\u30a6\u30a4\u30eb\u30b9\u7531\u6765\u306e\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u304c\u5bbf\u4e3b\u30b2\u30ce\u30e0\u5185\u3078\u3068\u5f8c\u5929\u7684\u306b\u518d\u633f\u5165\u3059\u308b\u3053\u3068\u306b\u8d77\u56e0\u3057\u305f\u764c\u907a\u4f1d\u5b50\u6d3b\u6027\u5316\u306e\u53ef\u80fd\u6027\u3092\u8003\u3048\u3001pre-B\u30ea\u30f3\u30d1\u816b\u3092\u767a\u75c7\u3057\u305fSL\/Kh\u30de\u30a6\u30b9\u500b\u4f53\u306e<br>\u30ea\u30f3\u30d1\u816b\u7d44\u7e54\u7531\u6765\u306egenomic DNA\u3092\u7528\u3044\u3001Inverse PCR\u6cd5\u306b\u3088\u308aAKV-1\u306e\u633f\u5165\u90e8\u4f4d\u306e\u540c\u5b9a\u3092\u8a66\u307f\u305f\u3002AKV-1\u306e\u633f\u5165\u597d\u767a\u90e8\u4f4d\u3068\u3057\u3066\u306f\u3053\u308c\u307e\u3067<em>Stat5a<\/em>\u3001<em>Evi3<\/em>\u3001<em>c-myc<\/em>\u3001<em>N-myc<\/em>\u3001<em>Stat5b<\/em>\u306a\u3069\u304c\u540c\u5b9a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u4eca\u56de\u65b0\u305f\u306b\u30de\u30a6\u30b9\u7b2c7\u67d3\u8272\u4f53\u4e0a\u306e\u764c\u907a\u4f1d\u5b50<em>Hras1<\/em>\u306eexon1\u304a\u3088\u3073intron1\u9818\u57df\u304c\u633f\u5165\u597d\u767a\u90e8\u4f4d\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3002\u633f\u5165\u90e8\u4f4d\u306f\u8fd1\u63a5\u3059\u308b3\u304b\u6240\u306b\u9650\u5b9a\u3055\u308c\u3066\u304a\u308a\u3001\u540c\u90e8\u4f4d\u3078\u306eAKV-1\u633f\u5165\u306f\u30ea\u30f3\u30d1\u816b\u3092\u767a\u75c7\u3057\u305fSL\/Kh\u30de\u30a6\u30b9130\u500b\u4f53\u4e2d7\u500b\u4f53(5.4%)\u3067\u8a8d\u3081\u3089\u308c\u305f\u3002\u633f\u5165\u90e8\u4f4d\u306f<em>Hras1<\/em>\u907a\u4f1d\u5b50\u306e\u30bf\u30f3\u30d1\u30af\u7ffb\u8a33\u9818\u57df\u306e\u4e0a\u6d41\u306b\u4f4d\u7f6e\u3057\u3066\u304a\u308a\u3001\u7ffb\u8a33\u3055\u308c\u308b\u30bf\u30f3\u30d1\u30af\u306f\u6b20\u640d\u3084\u5909\u7570\u306e\u306a\u3044\u6a5f\u80fd\u7684\u306a\u30bf\u30f3\u30d1\u30af\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002AKV-1\u633f\u5165\u3042\u308a\u306e\u500b\u4f53\u306b\u304a\u3044\u3066<em>Hras1<\/em>\u907a\u4f1d\u5b50\u304a\u3088\u3073\u878d\u5408\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306e\u6709\u7121\u3092\u691c\u8a0e\u3057\u305f\u3068\u3053\u308d\u3001\u691c\u8a0e\u3057\u305f\u3059\u3079\u3066\u306e\u500b\u4f53\u3067<em>Hras1<\/em>\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u8a8d\u3081\u3089\u308c\u3001AKV-1\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306b\u3088\u308b\u767a\u73fe\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002AKV-1\u3068\u30de\u30a6\u30b9\u306e\u878d\u5408\u907a\u4f1d\u5b50\u306f\u691c\u8a0e\u3057\u305f4\u500b\u4f53\u4e2d2\u500b\u4f53\u3067<em>Hras1<\/em>\u907a\u4f1d\u5b50\u306eintron1\u9818\u57df\u306e\u4e00\u90e8\u304c\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u3055\u308c\u305fmRNA\u306e\u767a\u73fe\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u90e8\u4f4d\u306fAKV-1\u633f\u5165\u90e8\u4f4d\u306b\u3088\u3089\u305a\u5171\u901a\u3057\u3066\u3044\u305f\u3002<em>Hras1<\/em>\u907a\u4f1d\u5b50\u3078\u306eAKV-1\u306e\u633f\u5165\u306b\u3088\u308b\u30de\u30a6\u30b9\u5bbf\u4e3b\u3078\u306e\u5f71\u97ff\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u3001AKV-1\u633f\u5165\u3042\u308a\u306e\u500b\u4f53\u3068\u633f\u5165\u306a\u3057\u306e\u500b\u4f53\u3092\u7528\u3044\u3066<em>Hras1<\/em>\u907a\u4f1d\u5b50\u304a\u3088\u3073Hras1\u30bf\u30f3\u30d1\u30af\u306e\u767a\u73fe\u91cf\u3092\u691c\u8a0e\u3057\u305f\u3002\u907a\u4f1d\u5b50\u304a\u3088\u3073\u30bf\u30f3\u30d1\u30af\u306e\u767a\u73fe\u91cf\u306fAKV-1\u633f\u5165\u3042\u308a\u306e\u500b\u4f53\u3067\u9ad8\u304f\u3001\u30bf\u30f3\u30d1\u30af\u767a\u73fe\u306e\u4e0a\u6607\u306f\u6709\u610f\u3067\u3042\u3063\u305f(P=0.0038)\u3002\u764c\u907a\u4f1d\u5b50<em>Hras1<\/em>\u306e\u30bf\u30f3\u30d1\u30af\u767a\u73fe\u306e\u4e0a\u6607\u304c\u3001\u30ea\u30f3\u30d1\u816b\u3092\u767a\u75c7\u3057\u305fSL\/Kh\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u305d\u306e\u767a\u764c\u306e\u6a5f\u5e8f\u306b\u4f55\u3089\u304b\u306e\u95a2\u9023\u6027\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<p class=\"has-background has-medium-font-size wp-block-paragraph\" style=\"background-color:#faf0c3\"><strong>B-lymphoblastic lymphoma\uff08B-LBL\uff09\u3092\u81ea\u7136\u767a\u75c7\u3059\u308bSL\/Kh\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u5185\u56e0\u6027\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u306e\u7279\u5b9a<\/strong> \u4e38\u5c71\u6cf0\u5f18<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"225\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image.jpeg\" alt=\"\" class=\"wp-image-14257\" style=\"width:300px;height:auto\" title=\"\u4fee\u58eb\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image.jpeg 300w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2010\/02\/image-115x86.jpeg 115w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">SL\/Kh\u30de\u30a6\u30b9\u306fproto-SL\u3001AKR\u3092progenitor\u3068\u3059\u308b\u8fd1\u4ea4\u7cfb\u30de\u30a6\u30b9\u3067\u3001\u751f\u5f8c\u7d04\u534a\u5e74\u3067\u305d\u306e\u500b\u4f53\u306e90\uff05\u4ee5\u4e0a\u304cB\u7d30\u80de\u82bd\u7403\u578b\u30ea\u30f3\u30d1\u816b\u3092\u81ea\u7136\u767a\u75c7\u3059\u308b\u3002\u3053\u308c\u307e\u3067\u306e\u30b5\u30b6\u30f3\u30d6\u30ed\u30c3\u30c8(SB)\u89e3\u6790\u3067\u3001\u3053\u306e\u30de\u30a6\u30b9\u306f\u907a\u4f1d\u7684\u306b\u5c11\u306a\u304f\u3068\u30827\u30ab\u6240\u3078\u306e\u5185\u5728\u6027\u30de\u30a6\u30b9\u767d\u8840\u75c5\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\uff08MuLV\uff09\u306e\u633f\u5165\u3092\u7372\u5f97\u3057\u3066\u3044\u308b\u3068\u63a8\u5bdf\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u306eMuLV\u306e\u633f\u5165\u90e8\u4f4d\u3092\u7279\u5b9a\u3057\u3001\u305d\u306e\u633f\u5165\u304c\u8fd1\u508d\u907a\u4f1d\u5b50\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u304b\u3001\u305d\u308c\u304c\u30ea\u30f3\u30d1\u816b\u306e\u767a\u75c7\u3068\u95a2\u9023\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\u306b\u4eca\u56de\u306e\u7814\u7a76\u3092\u884c\u3063\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30a6\u30b9genome\u3092\u5236\u9650\u9175\u7d20\u3067\u5207\u65ad\u3057\u3001\u30bb\u30eb\u30d5\u30e9\u30a4\u30b2\u30fc\u30b7\u30e7\u30f3\u5f8c\u3001\u30a4\u30f3\u30d0\u30fc\u30b9PCR\u6cd5\u3092\u7528\u3044\u3066\u633f\u5165\u90e8\u306e\u5897\u5e45\u3092\u884c\u3063\u305f\u3002\u5f97\u3089\u308c\u305fPCR\u7523\u7269\u3092\u7528\u3044\u3066\u30c0\u30a4\u30ec\u30af\u30c8\u30b7\u30fc\u30b1\u30f3\u30b9\u3092\u884c\u3044\u3001\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3068\u6bd4\u8f03\u691c\u8a0e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u4ee5\u4e0b\u306e4\u304b\u6240\u306e\u633f\u5165\u90e8\u4f4d\u304c\u7279\u5b9a\u3067\u304d\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">a\uff1a\u67d3\u8272\u4f532H2\u4e0a\u3067\u3001\u633f\u5165\u90e8\u4f4d\u304b\u3089\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u5074\u306b10761 base\u306e\u3068\u3053\u308d\u306b\u907a\u4f1d\u5b50\u3001<em>Commd7<\/em>\u304c\u5b58\u5728\u3057\u305f\u3002<em>Commd7<\/em><em>\u306f<\/em>\u5168\u9577\u7d0414Kbp\u30677\u500b\u306eExon\u3092\u6301\u3064\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3002COMM domain\u306fNF-\u03baB\u306e\u898f\u5236\u3068\u3001\u9285\u4ee3\u8b1d\u306e\u8abf\u6574\u3092\u884c\u3063\u3066\u3044\u308bMURR1\u3068\u76f8\u540c\u6027\u304c\u3042\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">b\uff1a\u67d3\u8272\u4f5315F1\u4e0a\u3067\u3001\u633f\u5165\u90e8\u4f4d\u304b\u3089\u30c6\u30ed\u30e1\u30a2\u5074\u306b5646 base\u306e\u3068\u3053\u308d\u306b\u907a\u4f1d\u5b50\u3001<em>olfr234<\/em>\u304c\u5b58\u5728\u3057\u305f\u3002<em>olfr234<\/em>\u306f\u5168\u9577522bp\u306e\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u81ed\u3044\u306e\u611f\u77e5\u306b\u95a2\u4fc2\u3059\u308b\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">c\uff1a\u67d3\u8272\u4f537A1\u4e0a\u3067\u3001\u907a\u4f1d\u5b50<em>Gltscr1<\/em>\u306e\u7b2c5\u30a4\u30f3\u30c8\u30ed\u30f3\u9818\u57df\u306bMuLV\u306e\u633f\u5165\u90e8\u4f4d\u304c\u5b58\u5728\u3057\u305f\u3002<em>Gltscr1<\/em>\u306f\u5168\u957728Kbp\u306714\u500b\u306eExon\u3092\u6301\u3064\u907a\u4f1d\u5b50\u3067\u3001\u4e4f\u7a81\u8d77\u81a0\u816b\u306e\u767a\u75c7\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u304c\u3001\u8a73\u3057\u3044\u6a5f\u80fd\u306f\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3002\u30d2\u30c8\u3067\u306f\u8133\u3001\u809d\u81d3\u306a\u3069\u4e3b\u8981\u81d3\u5668\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">d\uff1a\u67d3\u8272\u4f531A5\u4e0a\u3067\u633f\u5165\u90e8\u4f4d\u304b\u3089\u30c6\u30ed\u30e1\u30a2\u5074\u306b42718 base\u306e\u3068\u3053\u308d\u306b\u907a\u4f1d\u5b50\u3001<em>Smap1<\/em>\u304c\u5b58\u5728\u3057\u305f\u3002<em>Smap1<\/em>\u306f\u5168\u957775Kbp\u306710\u500b\u306eExon\u3092\u6301\u3064\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3002\u9aa8\u9ac4\u306estromal\u7d30\u80de\u306e\u8868\u9762\u5206\u5b50\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u8d64\u8840\u7403\u7523\u751f\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u3046\u3061<em>Gltscr1<\/em>\u306f\u907a\u4f1d\u5b50\u5185\u306bMuLV\u306e\u633f\u5165\u90e8\u4f4d\u304c\u8a8d\u3081\u3089\u308c\u305f\u3053\u3068\u304b\u3089\u3001MuLV\u633f\u5165\u304c<em>Gltscr1<\/em>\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3057\u305f\u3002RT-PCR\u6cd5\u3092\u7528\u3044\u305f\u5b9a\u6027\u7684\u691c\u8a0e\u3067\u306fBALB\/c\u30de\u30a6\u30b9\u306e\u8133\u3001\u814e\u81d3\u3001\u809d\u81d3\u3001\u813e\u81d3\u3067\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002SL\/Kh\u30de\u30a6\u30b9\u306e\u8133\u3001\u813e\u81d3\u3067\u3082\u540c\u69d8\u306b\u767a\u73fe\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u3082<em>Gltscr1<\/em>\u306f\u4e3b\u8981\u81d3\u5668\u3067\u30d2\u30c8\u3068\u540c\u69d8\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b21\u306b\u3001<em>Gltscr1<\/em>\u306e\u767a\u73fe\u3092MuLV\u633f\u5165\u90e8\u4f4d\u306e5\u2019\u5074\uff08\u4e0a\u6d41\uff09\u30013\u2019\u5074\uff08\u4e0b\u6d41\uff09\u306b\u5206\u3051\u3066\u5b9a\u91cf\u7684\u306b\u691c\u8a0e\u3057\u305f\u3002\u4e0a\u6d41\u3067\u306f\u3001BALB\/c\u30de\u30a6\u30b9\u306e\u813e\u81d3\u3001SL\/Kh\u30de\u30a6\u30b9\u306e\u8133\u3001\u813e\u81d3\u3001\u30ea\u30f3\u30d1\u816b\u3067\u767a\u73fe\u304c\u691c\u51fa\u3067\u304d\u305f\u3082\u306e\u306e\u3001BALB\/c\u306e\u8133\u3067\u306f\u767a\u73fe\u304c\u691c\u51fa\u3067\u304d\u306a\u304b\u3063\u305f\u3002\u4e0b\u6d41\u3067\u306fSL\/Kh\u30de\u30a6\u30b9\u306e\u30ea\u30f3\u30d1\u816b\u3067\u5fae\u5f31\u306a\u691c\u51fa\u304c\u3067\u304d\u305f\u3082\u306e\u306e\u3001\u691c\u8a0e\u3057\u305f\u4ed6\u306esample\u3067\u306f\u691c\u51fa\u3067\u304d\u306a\u304b\u3063\u305f\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u3057\u3066\u7528\u3044\u305fBALB\/c\u30de\u30a6\u30b9\u3067\u306e\u767a\u73fe\u304c\u691c\u51fa\u3067\u304d\u306a\u304b\u3063\u305f\u306e\u3067\u3001MuLV\u633f\u5165\u306b\u3088\u308b\u5f71\u97ff\u3092\u5224\u65ad\u3059\u308b\u306b\u306f\u81f3\u3089\u306a\u304b\u3063\u305f\u3002<\/p>\n\n\n\n<p class=\"has-text-align-left wp-block-paragraph\"><em>Gltscr1<\/em>\u5185\u3078\u306eMuLV\u633f\u5165\u304c\u30ea\u30f3\u30d1\u816b\u306e\u767a\u75c7\u3068\u95a2\u4fc2\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u5f15\u304d\u7d9a\u304d\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u764cHras1\u907a\u4f1d\u5b50\u306fSL\/Kh\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u30ea\u30f3\u30d1\u816b\u767a\u75c7\u6642\u306b\u307f\u3089\u308c\u308b\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u633f\u5165\u597d\u767a\u90e8\u4f4d\u306e\u3072\u3068\u3064\u3067\u3042\u308b\u3000\u91d1\u8c37\u548c\u54c9 SL\/Kh\u30de\u30a6\u30b9\u306fproto-SL\u3001AKR\u3092progenitor\u3068\u3059\u308b\u8fd1\u4ea4\u7cfb\u30de\u30a6\u30b9\u3067\u300190\uff05\u4ee5\u4e0a\u304c6 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14257,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,19],"tags":[],"class_list":["post-1367","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-36","category-19"],"_links":{"self":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1367"}],"version-history":[{"count":16,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1367\/revisions"}],"predecessor-version":[{"id":14260,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1367\/revisions\/14260"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=\/wp\/v2\/media\/14257"}],"wp:attachment":[{"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1367"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}