{"id":13538,"date":"2025-08-28T05:39:00","date_gmt":"2025-08-27T20:39:00","guid":{"rendered":"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=13538"},"modified":"2026-04-15T16:22:19","modified_gmt":"2026-04-15T07:22:19","slug":"%e3%83%92%e3%83%88%e8%83%9a%e3%81%ae%e4%bd%93%e8%bb%b8%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e3%81%ae%e8%ab%96%e6%96%87%e3%81%8cbirth-defect-research%e3%81%ab%e5%8f%97%e8%ab%be","status":"publish","type":"post","link":"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/?p=13538","title":{"rendered":"\u30d2\u30c8\u80da\u306e\u300c\u4f53\u306e\u5411\u304d\u300d\u306e\u591a\u69d8\u6027\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>\u85e4\u4e95\u52a9\u6559\u3089<\/strong>\u304c\u3001\u30d2\u30c8\u80da\u306e\u767a\u751f\u521d\u671f\u306b\u307f\u3089\u308c\u308b<strong>\u4f53\u8ef8\u306e\u5411\u304d<\/strong>\u306b\u3064\u3044\u3066\u5927\u898f\u6a21\u306b\u8abf\u3079\u3001\u30d2\u30c8\u3067\u306f\u30de\u30a6\u30b9\u306e\u3088\u3046\u306b\u4e00\u65b9\u5411\u3078\u6c7a\u307e\u3063\u305f\u4f53\u8ef8\u30d1\u30bf\u30fc\u30f3\u304c\u3042\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001<strong>\u3055\u307e\u3056\u307e\u306a\u5411\u304d\u304c\u5b58\u5728\u3059\u308b<\/strong>\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u6210\u679c\u306f\u30012025\u5e749\u67085\u65e5\u306b <em>Birth Defects Research<\/em> \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u3069\u3093\u306a\u7814\u7a76\u304b<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"163\" src=\"https:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-400x163.png\" alt=\"\" class=\"wp-image-13540\" style=\"width:620px\" srcset=\"http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-400x163.png 400w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-610x249.png 610w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-115x47.png 115w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-768x313.png 768w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14-150x61.png 150w, http:\/\/pathology.hs.med.kyoto-u.ac.jp\/wp-content\/uploads\/2025\/09\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-08-25-11.34.14.png 1318w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u767a\u751f\u521d\u671f\u306e\u80da\u306f\u3001\u982d\u304b\u3089\u5c3e\u306b\u304b\u3051\u3066\u5c11\u3057\u306d\u3058\u308c\u305f\u3088\u3046\u306a\u5f62\u3092\u3068\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<br>\u30de\u30a6\u30b9\u3067\u306f\u3001\u3053\u306e\u4f53\u306e\u8ef8\u304c\u901a\u5e38<strong>\u53f3\u5dfb\u304d<\/strong>\u306b\u306a\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u5de6\u53f3\u8ef8\u5f62\u6210\u3068\u306e\u95a2\u9023\u3082\u8b70\u8ad6\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u30d2\u30c8\u80da\u3067\u306f\u3001\u3053\u3046\u3057\u305f<strong>\u4f53\u306e\u5411\u304d\u306b\u6c7a\u307e\u3063\u305f\u30d1\u30bf\u30fc\u30f3\u304c\u3042\u308b\u306e\u304b\u3069\u3046\u304b<\/strong>\u304c\u3001\u3053\u308c\u307e\u3067\u3088\u304f\u5206\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<br>\u305d\u3053\u3067\u4eca\u56de\u3001\u308f\u308c\u308f\u308c\u306f\u4eac\u90fd\u5927\u5b66\u306e<strong>\u4eac\u90fd\u30b3\u30ec\u30af\u30b7\u30e7\u30f3<\/strong>\u306b\u53ce\u8535\u3055\u308c\u305f\u30d2\u30c8\u80da\u6a19\u672c\u306eMRI\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001\u767a\u751f\u521d\u671f\u306e\u4f53\u8ef8\u3092\u7cfb\u7d71\u7684\u306b\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bfe\u8c61\u3068\u3057\u305f\u306e\u306f\u3001<strong>Carnegie Stage\uff08CS\uff0913\u301c17<\/strong>\u306e<strong>545\u4f8b<\/strong>\u3067\u3059\u3002<br>\u982d\u90e8\u3068\u5c3e\u90e8\u306e\u4f4d\u7f6e\u95a2\u4fc2\u304b\u3089\u3001\u4f53\u8ef8\u3092<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u53f3\u5dfb\u304d\uff08RH\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u5de6\u5dfb\u304d\uff08LH\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u4e2d\u9593\u578b\uff08M\uff09<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u306b\u5206\u985e\u3057\u3066\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u308f\u304b\u3063\u305f\u3053\u3068<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u89e3\u6790\u306e\u7d50\u679c\u3001\u30d2\u30c8\u80da\u306e\u4f53\u8ef8\u306b\u306f<strong>\u304b\u306a\u308a\u5e45\u5e83\u3044\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3<\/strong>\u304c\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u767a\u751f\u6bb5\u968e\u3054\u3068\u306b\u307f\u308b\u3068\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CS13\u3067\u306f\u53f3\u5dfb\u304d\u304c\u3084\u3084\u591a\u3044<\/strong><\/li>\n\n\n\n<li><strong>CS14\u3067\u306f\u53f3\u5dfb\u304d\u3068\u5de6\u5dfb\u304d\u304c\u307b\u307c\u540c\u3058\u304f\u3089\u3044<\/strong><\/li>\n\n\n\n<li><strong>CS15\u4ee5\u964d\u3067\u306f\u5de6\u5dfb\u304d\u304c\u591a\u304f\u306a\u308b<\/strong><\/li>\n\n\n\n<li>\u767a\u751f\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u3001<strong>\u4e2d\u9593\u578b\uff08\u3088\u308a\u307e\u3063\u3059\u3050\u306a\u4f53\u8ef8\uff09\u304c\u5897\u3048\u3066\u3044\u304f<\/strong><\/li>\n\n\n\n<li><strong>CS17\u3067\u306f\u7d0470%\u304c\u4e2d\u9593\u578b<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u50be\u5411\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001\u30d2\u30c8\u3067\u306f\u300c\u3053\u308c\u304c\u6a19\u6e96\u7684\u306a\u5411\u304d\u300d\u3068\u8a00\u3044\u5207\u308c\u308b\u307b\u3069\u5358\u7d14\u3067\u306f\u306a\u304f\u3001<strong>\u767a\u751f\u306e\u9014\u4e2d\u3067\u306f\u81ea\u7136\u306a\u591a\u69d8\u6027\u304c\u3042\u308b<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u5185\u81d3\u306e\u5de6\u53f3\u6027\u3068\u306e\u95a2\u4fc2\u3082\u8abf\u3079\u307e\u3057\u305f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u5fc3\u81d3\u3001\u80c3\u3001\u809d\u81d3\u3001\u8178\u306a\u3069\u3001\u5de6\u53f3\u5dee\u3092\u3082\u3064\u5185\u81d3\u306b\u3064\u3044\u3066\u3082\u4e00\u90e8\u306e\u6a19\u672c\u3067\u8a73\u3057\u304f\u8abf\u3079\u307e\u3057\u305f\u3002<br>\u305d\u306e\u7d50\u679c\u3001\u4f53\u8ef8\u304c\u53f3\u5dfb\u304d\u3067\u3082\u5de6\u5dfb\u304d\u3067\u3082\u4e2d\u9593\u578b\u3067\u3082\u3001<strong>\u5185\u81d3\u306e\u5de6\u53f3\u914d\u7f6e\u306f\u304a\u304a\u3080\u306d\u5171\u901a<\/strong>\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3053\u3068\u304b\u3089\u3001<strong>\u5916\u304b\u3089\u898b\u305f\u4f53\u306e\u5411\u304d<\/strong>\u3068\u3001<strong>\u5185\u81d3\u306e\u5de6\u53f3\u6027<\/strong>\u3068\u306f\u3001\u5fc5\u305a\u3057\u3082\u305d\u306e\u307e\u307e\u5bfe\u5fdc\u3057\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u7814\u7a76\u306e\u610f\u5473<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30a6\u30b9\u306f\u767a\u751f\u5b66\u7814\u7a76\u3067\u975e\u5e38\u306b\u3088\u304f\u4f7f\u308f\u308c\u308b\u30e2\u30c7\u30eb\u52d5\u7269\u3067\u3059\u304c\u3001\u4eca\u56de\u306e\u7d50\u679c\u306f\u3001<strong>\u30de\u30a6\u30b9\u3067\u77e5\u3089\u308c\u3066\u3044\u308b\u5f62\u614b\u30d1\u30bf\u30fc\u30f3\u3092\u305d\u306e\u307e\u307e\u30d2\u30c8\u306b\u5f53\u3066\u306f\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044<\/strong>\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u30d2\u30c8\u80da\u306e\u4f53\u8ef8\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u308c\u307e\u3067\u5199\u771f\u3084\u30b9\u30b1\u30c3\u30c1\u3067\u500b\u5225\u306b\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u3063\u3066\u3082\u3001<strong>500\u4f8b\u3092\u8d85\u3048\u308b\u6a19\u672c\u3092\u7528\u3044\u3066\u7cfb\u7d71\u7684\u306b\u8abf\u3079\u305f\u7814\u7a76\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f<\/strong>\u3002<br>\u4eca\u56de\u306e\u7814\u7a76\u306f\u3001\u30d2\u30c8\u521d\u671f\u767a\u751f\u306b\u304a\u3051\u308b\u4f53\u306e\u5f62\u3065\u304f\u308a\u306b<strong>\u4e88\u60f3\u4ee5\u4e0a\u306e\u591a\u69d8\u6027\u304c\u3042\u308b<\/strong>\u3053\u3068\u3092\u3001\u5927\u898f\u6a21\u30c7\u30fc\u30bf\u304b\u3089\u793a\u3057\u305f\u70b9\u306b\u610f\u7fa9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u3001\u3053\u3046\u3057\u305f\u77e5\u898b\u306f\u3001\u30d2\u30c8\u306e\u5de6\u53f3\u8ef8\u5f62\u6210\u3084\u5148\u5929\u7570\u5e38\u306e\u7406\u89e3\u306b\u3064\u306a\u304c\u308b\u57fa\u790e\u8cc7\u6599\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8ad6\u6587\u60c5\u5831<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Title<\/strong><br><em>Helical Body Axis Orientations in Human Embryonic Development<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Authors<\/strong><br>Sena Fujii, Shigehito Yamada, Tetsuya Takakuwa<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Journal<\/strong><br><em>Birth Defects Research<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>First published<\/strong><br>2025\u5e749\u67085\u65e5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>DOI<\/strong><br><a class=\"\" href=\"https:\/\/doi.org\/10.1002\/bdr2.2527\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/bdr2.2527<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u3072\u3068\u3053\u3068<\/h2>\n\n\n\n<p 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